BDBM50146549 CHEMBL3764222

SMILES COc1cccc(CON)c1

InChI Key InChIKey=DNGAZMVOQCQJIG-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50146549   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146549(CHEMBL3764222)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetAlanine--glyoxylate aminotransferase(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50146549(CHEMBL3764222)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant wild type His-tagged AGT (unknown origin) expressed in Escherichia coli BL21 using L-alanine and glyoxylate as a substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAlanine--glyoxylate aminotransferase(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50146549(CHEMBL3764222)
Affinity DataKi:  40nMAssay Description:Inhibition of recombinant wild type His-tagged AGT (unknown origin) expressed in Escherichia coli BL21 assessed as inhibition constant using L-alanin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed