BDBM50146478 CHEMBL98390::N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide

SMILES CC(C)CN1CCC(CC(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)N(O)C=O)CC1

InChI Key InChIKey=AYWKRESAZCSENH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50146478   

TargetMatrix metalloproteinase-9(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146478(N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146478(N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2...)
Affinity DataIC50: 350nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146478(N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146478(N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146478(N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146478(N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2...)
Affinity DataIC50: 12nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed