BDBM50146461 CHEMBL3765807

SMILES NOCc1cccc(Cl)c1

InChI Key InChIKey=PZPCEIVCWGWHCC-UHFFFAOYSA-N

Data  2 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50146461   

TargetCatalase(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of catalase (unknown origin) using hydrogen peroxide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataIC50: 114nMAssay Description:Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production treated with 5-fold serial dilution beginning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataIC50: 77nMAssay Description:Inhibition of doxycycline-induced human IDO1 expressed in Trex cells assessed as reduction in kynurenine production treated with 5-fold serial diluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataIC50: 134nMAssay Description:Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production treated with 3-fold serial dilution beginning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetAlanine--glyoxylate aminotransferase(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant wild type His-tagged AGT (unknown origin) expressed in Escherichia coli BL21 using L-alanine and glyoxylate as a substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataKi:  154nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by Michaelis-Menton...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetAlanine--glyoxylate aminotransferase(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of recombinant wild type His-tagged AGT (unknown origin) expressed in Escherichia coli BL21 assessed as inhibition constant using L-alanin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed