BDBM50146453 (E)-3-(4-Methoxy-phenyl)-acrylic acid::3-(4-methoxyphenyl)acrylic acid::4-Methoxycinnamic acid::CHEMBL95770::para-methoxycinnamic acid

SMILES COc1ccc(\C=C\C(O)=O)cc1

InChI Key InChIKey=AFDXODALSZRGIH-UHFFFAOYSA-N

Data  10 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50146453   

TargetPolyphenol oxidase 2(White button mushroom)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50146453(3-(4-methoxyphenyl)acrylic acid | para-methoxycinn...)
Affinity DataIC50: 4.10E+5nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50146453(3-(4-methoxyphenyl)acrylic acid | para-methoxycinn...)
Affinity DataIC50: 4.10E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as 3,4-dihydroxy-L-phenylalanine oxidationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50146453(3-(4-methoxyphenyl)acrylic acid | para-methoxycinn...)
Affinity DataIC50: 4.10E+5nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50146453(3-(4-methoxyphenyl)acrylic acid | para-methoxycinn...)
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of mushroom tyrosinase after 25 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50146453(3-(4-methoxyphenyl)acrylic acid | para-methoxycinn...)
Affinity DataIC50: 4.10E+5nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50146453(3-(4-methoxyphenyl)acrylic acid | para-methoxycinn...)
Affinity DataIC50: 4.10E+5nMAssay Description:Inhibition of mashroom tyrosinase assessed as oxidation of L-DOPA by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50146453(3-(4-methoxyphenyl)acrylic acid | para-methoxycinn...)
Affinity DataIC50: 4.10E+5nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146453(3-(4-methoxyphenyl)acrylic acid | para-methoxycinn...)
Affinity DataIC50: 7.60E+5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 using 4-nitrophenylacetate as substrate pretreated for 15 mins prior to test by spectrophotometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146453(3-(4-methoxyphenyl)acrylic acid | para-methoxycinn...)
Affinity DataIC50: 8.50E+5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 using 4-nitrophenylacetate as substrate pretreated for 15 mins prior to test by spectrophotometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2019
Entry Details Article
PubMed
TargetAlpha-glucosidase MAL62(Baker's yeast)TBA
LigandPNGBDBM50146453(3-(4-methoxyphenyl)acrylic acid | para-methoxycinn...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of baker's yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article