BDBM50146219 6-Hydroxy-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid ethyl ester::CHEMBL94080

SMILES CCOC(=O)N1CCc2cc(O)ccc2C1c1ccc(OCCN2CCCC2)cc1

InChI Key InChIKey=KUEZQAQZOUTJKW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146219   

TargetEstrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146219(6-Hydroxy-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-...)
Affinity DataIC50: 44nMAssay Description:In vitro concentration required to inhibit [3H]estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146219(6-Hydroxy-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-...)
Affinity DataIC50: 293nMAssay Description:In vitro concentration required to inhibit [3H]estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed