BDBM50146058 Benzo[de]isochromene-1,3-dione::CHEMBL316059

SMILES O=C1OC(=O)c2cccc3cccc1c23

InChI Key InChIKey=GRSMWKLPSNHDHA-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50146058   

TargetNAD-dependent histone deacetylase SIR2(Baker's yeast)
Fred Hutchinson Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50146058(Benzo[de]isochromene-1,3-dione | CHEMBL316059)
Affinity DataIC50: 8.80E+3nMAssay Description:In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50146058(Benzo[de]isochromene-1,3-dione | CHEMBL316059)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human thymidylate synthase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli (strain K12))
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50146058(Benzo[de]isochromene-1,3-dione | CHEMBL316059)
Affinity DataKi: >2.94E+5nMAssay Description:Inhibition of Escherichia coli thymidylate synthase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed