BDBM50146043 CHEMBL543372::[(1R,3S)-3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1-yl]-methyl-amine; hydrochloride

SMILES CN[C@@H]1C[C@H](c2ccc(OC)cc12)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=SPMRKSIEUHZTAA-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50146043   

TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50146043([(1R,3S)-3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [125I]RTI-55 from serotonin transporter of frozen rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50146043([(1R,3S)-3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1...)
Affinity DataKi:  7nMAssay Description:Reuptake inhibitory activity against NE transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50146043([(1R,3S)-3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1...)
Affinity DataKi:  9nMAssay Description:Binding affinity for DA transporter using [125I]RTI-55 in frozen rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50146043([(1R,3S)-3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1...)
Affinity DataKi:  12nMAssay Description:Reuptake inhibitory activity against dopamine DA transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50146043([(1R,3S)-3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1...)
Affinity DataKi:  19nMAssay Description:Reuptake inhibitory activity against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50146043([(1R,3S)-3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1...)
Affinity DataKi:  34nMAssay Description:Reuptake inhibitory activity against NE transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed