BDBM50146038 CHEMBL554565::[(1S,3R)-3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1-yl]-methyl-amine; hydrochloride

SMILES CN[C@H]1C[C@@H](c2ccc(OC)cc12)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=SPMRKSIEUHZTAA-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50146038   

TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50146038([(1S,3R)-3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1...)
Affinity DataKi:  51nMAssay Description:Displacement of [125I]RTI-55 from serotonin transporter of frozen rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50146038([(1S,3R)-3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1...)
Affinity DataKi:  109nMAssay Description:Reuptake inhibitory activity against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50146038([(1S,3R)-3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1...)
Affinity DataKi:  600nMAssay Description:Reuptake inhibitory activity against dopamine DA transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50146038([(1S,3R)-3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1...)
Affinity DataKi:  600nMAssay Description:Binding affinity for DA transporter using [125I]RTI-55 in frozen rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50146038([(1S,3R)-3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1...)
Affinity DataKi:  650nMAssay Description:Reuptake inhibitory activity against NE transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50146038([(1S,3R)-3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1...)
Affinity DataKi:  820nMAssay Description:Displacement of from norepinephrine transporter of frozen rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed