BDBM50145175 CHEMBL3764798

SMILES C[C@H](NC(=O)c1[nH]nc2cc(NCc3cccc(NC(=O)c4cc(cc(c4)C(F)(F)F)-n4cncc4C)c3)ccc12)C(N)=O

InChI Key InChIKey=KCKJDURDBLOYPJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50145175   

TargetSerine/threonine-protein kinase B-raf(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50145175(CHEMBL3764798)
Affinity DataIC50: 9.45E+3nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50145175(CHEMBL3764798)
Affinity DataIC50: 3.86E+4nMAssay Description:Inhibition of CRAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50145175(CHEMBL3764798)
Affinity DataIC50: 7.82E+3nMAssay Description:Inhibition of BRAF V599E mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed