BDBM50144947 2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-hydroxymethyl-3-methoxy-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one::CHEMBL308370

SMILES CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c1nc(N)[nH]c2=O

InChI Key InChIKey=OVYNGSFVYRPRCG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144947   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144947(2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-hydroxymethyl...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition HCV NS5B-mediated RNA synthesisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144947(2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-hydroxymethyl...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition HCV RNA replicationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed