BDBM50144535 (2S,3R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-1-carbonyl]-3-piperidin-4-ylmethyl-azetidine-2-carboxylic acid::(R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-1-carbonyl]-3-piperidin-4-ylmethyl-azetidine-2-carboxylic acid::CHEMBL70350

SMILES OC(=O)[C@@H]1[C@@H](CC2CCNCC2)C(=O)N1C(=O)N1CCN(CC1)C(=O)CCCCCc1ccccc1

InChI Key InChIKey=BOPGBYFJKNADGK-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50144535   

TargetSerine protease 1(Bovine)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144535((R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-1-ca...)
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144535((R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-1-ca...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against human tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144535((R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-1-ca...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Rat)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144535((R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-1-ca...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144535((R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-1-ca...)
Affinity DataIC50: 970nMAssay Description:Inhibitory activity against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144535((R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-1-ca...)
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTissue-type plasminogen activator(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144535((R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-1-ca...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibitory activity against tissue type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed