BDBM50143967 CHEMBL60568::N-Benzyl-2-{4-[3-(2,6-dimethyl-phenoxy)-2-hydroxy-propyl]-piperazin-1-yl}-2-p-tolyl-acetamide

SMILES Cc1ccc(cc1)C(N1CCN(CC(O)COc2c(C)cccc2C)CC1)C(=O)NCc1ccccc1

InChI Key InChIKey=GHFZLQFZZCWSMK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143967   

LigandPNGBDBM50143967(N-Benzyl-2-{4-[3-(2,6-dimethyl-phenoxy)-2-hydroxy-...)
Affinity DataIC50: 325nMAssay Description:In vitro inhibition of [3H]batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50143967(N-Benzyl-2-{4-[3-(2,6-dimethyl-phenoxy)-2-hydroxy-...)
Affinity DataKi:  2.00E+3nMAssay Description:Predictive competitive inhibition of cytochrome P450 2D6 was determined in silicoMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed