BDBM50143831 (E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-4,5,6,7-tetrahydro-benzooxazol-2-yl]-acrylic acid::CHEMBL64222

SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1CCCc2oc(\C=C\C(O)=O)nc12

InChI Key InChIKey=FGQBLCYSBHFGFH-UHFFFAOYSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50143831   

TargetRetinoic acid receptor RXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143831((E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataEC50:  749nMAssay Description:Effective concentration for lipogenesis induced by retinoid X receptor alpha in C3H10T1/2 clone 8 fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRetinoic acid receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143831((E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration for retinoic acid receptor alpha induced lipogenesis in C3H10T1/2 clone 8 fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143831((E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataEC50:  42nMAssay Description:Effective concentration for Retinoid X receptor alpha activity in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143831((E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  158nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRetinoic acid receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143831((E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed