BDBM50142851 CHEMBL3759868

SMILES COc1cc2ncnc(Nc3ccccc3Br)c2cc1OCCCCC(=O)NO

InChI Key InChIKey=DMPZTBXGEVKONB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142851   

TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142851(CHEMBL3759868)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin) preincubated for 5 mins followed by addition of ATP/gastrin precursor(Tyr87) biotinylated peptide cocktail incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142851(CHEMBL3759868)
Affinity DataIC50: 74nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed