BDBM50142838 CHEMBL3758697

SMILES COc1cc2ncnc(Nc3ccc(Br)cc3)c2cc1OCCCCCC(=O)NO

InChI Key InChIKey=BGZHWIUOIXXKJR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50142838   

TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142838(CHEMBL3758697)
Affinity DataIC50: 153nMAssay Description:Inhibition of VEGFR2 (unknown origin) preincubated for 5 mins followed by addition of ATP/gastrin precursor(Tyr87) biotinylated peptide cocktail incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142838(CHEMBL3758697)
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142838(CHEMBL3758697)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142838(CHEMBL3758697)
Affinity DataIC50: 74nMAssay Description:Inhibition of VGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed