BDBM50142796 CHEMBL3759186

SMILES COc1cc2ncnc(Nc3ccc(Br)cc3)c2cc1OCCCCCCC(=O)NO

InChI Key InChIKey=BNWIAUUKBJSRSZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50142796   

TargetHistone deacetylase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142796(CHEMBL3759186)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142796(CHEMBL3759186)
Affinity DataIC50: 74nMAssay Description:Inhibition of VEGFR2 (unknown origin) preincubated for 5 mins followed by addition of ATP/gastrin precursor(Tyr87) biotinylated peptide cocktail incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142796(CHEMBL3759186)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142796(CHEMBL3759186)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of HDAC2 (unknown origin) preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142796(CHEMBL3759186)
Affinity DataIC50: 16nMAssay Description:Inhibition of HDAC6 (unknown origin) preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142796(CHEMBL3759186)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of HDAC8 (unknown origin) preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142796(CHEMBL3759186)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142796(CHEMBL3759186)
Affinity DataIC50: 74nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed