BDBM50142566 4-[9-(4-Methyl-thiazol-2-yl)-8-oxo-5,6,7,8-tetrahydro-2,7a-diaza-dibenzo[a,c]cyclohepten-11-yl]-benzonitrile::CHEMBL44916

SMILES Cc1csc(n1)-c1cc(-c2ccc(cc2)C#N)c2-c3cnccc3CCCn2c1=O

InChI Key InChIKey=QQKKCXYUPJTQBC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142566   

TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142566(4-[9-(4-Methyl-thiazol-2-yl)-8-oxo-5,6,7,8-tetrahy...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142566(4-[9-(4-Methyl-thiazol-2-yl)-8-oxo-5,6,7,8-tetrahy...)
Affinity DataKi:  5.40nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed