BDBM50142564 11-(1-Methyl-1H-imidazol-2-yl)-9-(4-methyl-thiazol-2-yl)-6,7-dihydro-5H-2,7a-diaza-dibenzo[a,c]cyclohepten-8-one::CHEMBL44985

SMILES Cc1csc(n1)-c1cc(-c2nccn2C)c2-c3cnccc3CCCn2c1=O

InChI Key InChIKey=XRIXNULAASCVLG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142564   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142564(11-(1-Methyl-1H-imidazol-2-yl)-9-(4-methyl-thiazol...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]Ro-151788 from human GABA-A receptor alpha-1-beta-3-gamma-2 subunits expressed in L(tk) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142564(11-(1-Methyl-1H-imidazol-2-yl)-9-(4-methyl-thiazol...)
Affinity DataKi:  17nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed