BDBM50142528 CHEMBL296351::N-Benzothiazol-2-yl-3,4,5-trihydroxy-benzamide

SMILES Oc1cc(cc(O)c1O)C(=O)Nc1nc2ccccc2s1

InChI Key InChIKey=WHTLHKPXPPUCSN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142528   

TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142528(N-Benzothiazol-2-yl-3,4,5-trihydroxy-benzamide | C...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed