BDBM50141455 CHEMBL285251::N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-2-yl]-3-((E)-phenyl)-acrylamide

SMILES Nc1nc(NC(=O)\C=C\c2ccccc2)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

InChI Key InChIKey=DDCUXRNACUVAKE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50141455   

TargetAdenosine receptor A1(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141455(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141455(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  900nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor in stably transfected HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141455(N-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydrox...)
Affinity DataKi:  4.10E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor in stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed