BDBM50140792 1-(4-Cyano-2-hydroxy-phenyl)-3-phenyl-urea::1-(4-cyano-2-hydroxyphenyl)-3-phenylurea::CHEMBL25573

SMILES Oc1cc(ccc1NC(=O)Nc1ccccc1)C#N

InChI Key InChIKey=XRZHCICQICNYCB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50140792   

TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140792(1-(4-Cyano-2-hydroxy-phenyl)-3-phenyl-urea | 1-(4-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 2 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140792(1-(4-Cyano-2-hydroxy-phenyl)-3-phenyl-urea | 1-(4-...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 1 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140792(1-(4-Cyano-2-hydroxy-phenyl)-3-phenyl-urea | 1-(4-...)
Affinity DataIC50: 200nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed