BDBM50140708 5-(2-methoxyphenyl)-3-(2-methylphenyl)-(3R,3aS,6aR)-spiro[perhydrofuro[3,4-c]pyrrole-1,2'-(2',3'-dihydro-1'H-indene)]-1',3',4,6-tetraone::CHEMBL26600

SMILES COc1ccccc1-n1c(O)c2C(OC3(C(=O)c4ccccc4C3=O)c2c1O)c1ccccc1C

InChI Key InChIKey=WKIPIHOSPIAZQO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50140708   

TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140708(5-(2-methoxyphenyl)-3-(2-methylphenyl)-(3R,3aS,6aR...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140708(5-(2-methoxyphenyl)-3-(2-methylphenyl)-(3R,3aS,6aR...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140708(5-(2-methoxyphenyl)-3-(2-methylphenyl)-(3R,3aS,6aR...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed