BDBM50139758 (2-Naphthalen-2-yl-1-naphthalen-1-yl-2-oxo-ethyl)-phosphonic acid::1-(naphthalen-1-yl)-2-(naphthalen-2-yl)-2-oxoethylphosphonic acid::CHEMBL424224

SMILES c1ccc2cc(ccc2c1)C(=O)[C@@H](c3cccc4c3cccc4)P(=O)(O)O

InChI Key InChIKey=OFHMUASCSJJNNA-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50139758   

TargetCathepsin G(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50139758(1-(naphthalen-1-yl)-2-(naphthalen-2-yl)-2-oxoethyl...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory activity against human Cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstatic acid phosphatase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50139758(1-(naphthalen-1-yl)-2-(naphthalen-2-yl)-2-oxoethyl...)
Affinity DataIC50: 6.00E+3nMAssay Description:Tested for 50% of inhibition of Osteoclastic acid phosphatase (OAP) activity, determined using dose-response curveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetChymase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50139758(1-(naphthalen-1-yl)-2-(naphthalen-2-yl)-2-oxoethyl...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of chymase in human mast cells using Suc-Ala-Ala-Pro-Phe-(p-nitroanilide) as substrate for 15 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed