BDBM50138977 CHEMBL419740::N-(3-Aminomethyl-phenyl)-acetamidin::N-(3-Aminomethyl-phenyl)-acetamidine

SMILES CC(=N)Nc1cccc(CN)c1

InChI Key InChIKey=XPQAJKGBNGGGQF-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50138977   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50138977(N-(3-Aminomethyl-phenyl)-acetamidine | N-(3-Aminom...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50138977(N-(3-Aminomethyl-phenyl)-acetamidine | N-(3-Aminom...)
Affinity DataIC50: 480nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50138977(N-(3-Aminomethyl-phenyl)-acetamidine | N-(3-Aminom...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human nNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50138977(N-(3-Aminomethyl-phenyl)-acetamidine | N-(3-Aminom...)
Affinity DataKi:  40nMAssay Description:Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed