BDBM50138751 5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,2,4]triazole-1-carboxylic acid methyl-phenyl-amide::CHEMBL131051::N-methyl-5-(methylthio)-N-phenyl-3-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazole-1-carboxamide

SMILES CSc1nc(nn1C(=O)N(C)c1ccccc1)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=RKKAABIABTWSCU-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50138751   

TargetPancreatic triacylglycerol lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138751(N-methyl-5-(methylthio)-N-phenyl-3-(4-(trifluorome...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was tested to inhibit pancreatic lipase (PL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138751(N-methyl-5-(methylthio)-N-phenyl-3-(4-(trifluorome...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was tested to inhibit hepatic lipase (HL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138751(N-methyl-5-(methylthio)-N-phenyl-3-(4-(trifluorome...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLipoprotein lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138751(N-methyl-5-(methylthio)-N-phenyl-3-(4-(trifluorome...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was tested to inhibit lipoprotein lipase (LPL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138751(N-methyl-5-(methylthio)-N-phenyl-3-(4-(trifluorome...)
Affinity DataIC50: 250nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138751(N-methyl-5-(methylthio)-N-phenyl-3-(4-(trifluorome...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138751(N-methyl-5-(methylthio)-N-phenyl-3-(4-(trifluorome...)
Affinity DataIC50: 5.00E+7nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138751(N-methyl-5-(methylthio)-N-phenyl-3-(4-(trifluorome...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of HSL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138751(N-methyl-5-(methylthio)-N-phenyl-3-(4-(trifluorome...)
Affinity DataIC50: 4.41nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed