BDBM50138747 (3-(4-chlorophenyl)-5-(cyclopropylmethylthio)-1H-1,2,4-triazol-1-yl)(piperidin-1-yl)methanone::CHEMBL336398::[3-(4-Chloro-phenyl)-5-cyclopropylmethylsulfanyl-[1,2,4]triazol-1-yl]-piperidin-1-yl-methanone

SMILES Clc1ccc(cc1)-c1nc(SCC2CC2)n(n1)C(=O)N1CCCCC1

InChI Key InChIKey=XWIIHZHUZCWNLW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50138747   

TargetHormone-sensitive lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138747([3-(4-Chloro-phenyl)-5-cyclopropylmethylsulfanyl-[...)
Affinity DataIC50: 200nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138747([3-(4-Chloro-phenyl)-5-cyclopropylmethylsulfanyl-[...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138747([3-(4-Chloro-phenyl)-5-cyclopropylmethylsulfanyl-[...)
Affinity DataIC50: 900nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138747([3-(4-Chloro-phenyl)-5-cyclopropylmethylsulfanyl-[...)
Affinity DataIC50: 3.53nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed