BDBM50138739 4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazol-3-yl)-phenyl]-benzamide::4-tert-butyl-N-(4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)phenyl)benzamide::CHEMBL339297

SMILES COc1nn(-c2ccc(NC(=O)c3ccc(cc3)C(C)(C)C)cc2)c(=O)o1

InChI Key InChIKey=QPUXQWSDBKIGCJ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50138739   

TargetCholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-butyl-N-(4-(5-methoxy-2-oxo-1,3,4-oxadiazol...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-butyl-N-(4-(5-methoxy-2-oxo-1,3,4-oxadiazol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested to inhibit pancreatic lipase (PL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-butyl-N-(4-(5-methoxy-2-oxo-1,3,4-oxadiazol...)
Affinity DataIC50: 23nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLipoprotein lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-butyl-N-(4-(5-methoxy-2-oxo-1,3,4-oxadiazol...)
Affinity DataIC50: 200nMAssay Description:Compound was tested to inhibit lipoprotein lipase (LPL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-butyl-N-(4-(5-methoxy-2-oxo-1,3,4-oxadiazol...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-butyl-N-(4-(5-methoxy-2-oxo-1,3,4-oxadiazol...)
Affinity DataIC50: 1.80E+3nMAssay Description:Compound was tested to inhibit hepatic lipase (HL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-butyl-N-(4-(5-methoxy-2-oxo-1,3,4-oxadiazol...)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed