BDBM501385 US11026936, Compound A14

SMILES C[C@@H]1CN(CC[C@@H]1C1(CC1)c1nnc([nH]1)-c1ccccc1)C(=O)[C@@](C)(O)C(F)(F)F

InChI Key InChIKey=SARBZSHZVJZGBG-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501385   

LigandPNGBDBM501385(US11026936, Compound A14)
Affinity DataIC50: 130nMAssay Description:The PDC inactivation assay is performed in Greiner 384-well microtiter plates and is used for high throughput screen. 4 μl of PDHK2 (human, rec,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

LigandPNGBDBM501385(US11026936, Compound A14)
Affinity DataKd: <2nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent