BDBM50138161 CHEMBL321466::N-{1-[(3-Aminomethyl-phenylcarbamoyl)-methyl]-2-oxo-azepan-3-yl}-3,3-diphenyl-propionamide

SMILES NCc1cccc(NC(=O)CN2CCCCC(NC(=O)CC(c3ccccc3)c3ccccc3)C2=O)c1

InChI Key InChIKey=XLHDYTQMNPVLMS-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50138161   

TargetVitamin K-dependent protein C(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138161(N-{1-[(3-Aminomethyl-phenylcarbamoyl)-methyl]-2-ox...)
Affinity DataIC50: 170nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138161(N-{1-[(3-Aminomethyl-phenylcarbamoyl)-methyl]-2-ox...)
Affinity DataIC50: 170nMAssay Description:Compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138161(N-{1-[(3-Aminomethyl-phenylcarbamoyl)-methyl]-2-ox...)
Affinity DataIC50: 170nMAssay Description:Compound was tested for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTissue-type plasminogen activator(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138161(N-{1-[(3-Aminomethyl-phenylcarbamoyl)-methyl]-2-ox...)
Affinity DataIC50: 170nMAssay Description:Compound was tested for inhibition of human tissue type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138161(N-{1-[(3-Aminomethyl-phenylcarbamoyl)-methyl]-2-ox...)
Affinity DataIC50: 170nMAssay Description:Compound was tested for inhibition of human urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138161(N-{1-[(3-Aminomethyl-phenylcarbamoyl)-methyl]-2-ox...)
Affinity DataIC50: 170nMAssay Description:Compound was tested for inhibition of human alpha-thrombin (FIIa)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138161(N-{1-[(3-Aminomethyl-phenylcarbamoyl)-methyl]-2-ox...)
Affinity DataIC50: 170nMAssay Description:Compound was tested for inhibition of human trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138161(N-{1-[(3-Aminomethyl-phenylcarbamoyl)-methyl]-2-ox...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human tryptase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed