BDBM50137704 (S)-4-(S)-Hydroxy-2-methyl-6-phenyl-5-[(S)-2-((S)-4,4,4-trifluoro-2-hydroxy-butyrylamino)-propionylamino]-hexanoic acid {(S)-2-methyl-1-[(pyridin-4-ylmethyl)-carbamoyl]-propyl}-amide::CHEMBL84022

SMILES CC(C)[C@H](NC(=O)[C@H](C)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](O)CC(F)(F)F)C(=O)NCc1ccncc1

InChI Key InChIKey=DCMVDBRFPYSFOY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137704   

TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137704((S)-4-(S)-Hydroxy-2-methyl-6-phenyl-5-[(S)-2-((S)-...)
Affinity DataIC50: 220nMAssay Description:In vitro inhibitory activity against Beta-secretase 1 in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed