BDBM50137490 1-Cyclohexyl-2-thiophen-3-yl-1H-benzoimidazole-5-carboxylic acid::CHEMBL174564

SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccsc1

InChI Key InChIKey=BCYWSFMDAURAHE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50137490   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137490(1-Cyclohexyl-2-thiophen-3-yl-1H-benzoimidazole-5-c...)
Affinity DataIC50: 6.33E+3nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Poliovirus type 1 (strain Mahoney))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137490(1-Cyclohexyl-2-thiophen-3-yl-1H-benzoimidazole-5-c...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibitory activity against polio virus RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137490(1-Cyclohexyl-2-thiophen-3-yl-1H-benzoimidazole-5-c...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibitory activity against calf thymus RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed