BDBM50137480 1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-carboxylic acid::1-cyclohexyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxylic acid::CHEMBL174683

SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccn1

InChI Key InChIKey=VJHUUUYKIKSXKH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50137480   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137480(1-cyclohexyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(Poliovirus type 1 (strain Mahoney))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137480(1-cyclohexyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibitory activity against polio virus RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50137480(1-cyclohexyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibitory concentration against hepatitis C virus polymeraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137480(1-cyclohexyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137480(1-cyclohexyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibitory activity against calf thymus RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed