BDBM50137281 2-Benzenesulfonyl-6-hydroxy-7-methoxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide::CHEMBL148171::N,6-dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide

SMILES COc1cc2C(N(CCc2cc1O)S(=O)(=O)c1ccccc1)C(=O)NO

InChI Key InChIKey=JOGYGVFUVCZABB-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50137281   

TargetMatrix metalloproteinase-9(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137281(N,6-dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4...)
Affinity DataIC50: 100nMAssay Description:Inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137281(N,6-dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4...)
Affinity DataIC50: 867nMAssay Description:Inhibition of matrix metalloprotease-14 (MMP-14)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-15(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137281(N,6-dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4...)
Affinity DataIC50: 29nMAssay Description:Inhibition of matrix metalloprotease-15 (MMP-15)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-26(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137281(N,6-dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4...)
Affinity DataIC50: 146nMAssay Description:Inhibition of matrix metalloprotease-26 (MMP-26)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137281(N,6-dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4...)
Affinity DataIC50: 40nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137281(N,6-dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4...)
Affinity DataIC50: 595nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137281(N,6-dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4...)
Affinity DataIC50: 65nMAssay Description:Inhibition of matrix metalloprotease-12 (MMP-12)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137281(N,6-dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4...)
Affinity DataIC50: 27nMAssay Description:Inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137281(N,6-dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4...)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137281(N,6-dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4...)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed