BDBM50136492 6-Methoxy-2,3,4,9-tetrahydro-1H-beta-carboline::6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole::CHEMBL266084

SMILES COc1ccc2[nH]c3CNCCc3c2c1

InChI Key InChIKey=QYMDEOQLJUUNOF-UHFFFAOYSA-N

Data  4 KI  3 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50136492   

TargetAcetylcholinesterase(Human)
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50136492(6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50136492(6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Naresuan University

Curated by ChEMBL
LigandPNGBDBM50136492(6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...)
Affinity DataIC50: 2.27E+5nMAssay Description:Inhibition of electric eel AChE using acetylcholine iodide as substrate measured every 5 sec for 2 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDihydroorotase(Bacillus anthracis)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50136492(6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...)
Affinity DataKd:  6.75E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetDihydroorotase(Bacillus anthracis)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50136492(6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...)
Affinity DataKd:  5.88E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50136492(6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity for rat 5-hydroxytryptamine 2A receptor using [3H]DOBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50136492(6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...)
Affinity DataKi:  2.19E+3nMAssay Description:Binding affinity towards cloned rat 5-hydroxytryptamine 2C receptor from fundus tissue by [3H]mesulergine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50136492(6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...)
Affinity DataKi:  4.78E+3nMAssay Description:Binding affinity towards cloned rat 5-hydroxytryptamine 2A receptor by [3H]ketanserin displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50136492(6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...)
Affinity DataKi:  7.83E+3nMAssay Description:Binding affinity at alpha-2 adrenergic receptors of rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed