BDBM50135601 (S,E)-N1-(3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl)-N4-hydroxy-2-(2-methylpropylidene)succinamide 1::CHEMBL95237::N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-[2-methyl-prop-(E)-ylidene]-succinamide

SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C(\CC(=O)NO)=C\C(C)C

InChI Key InChIKey=IHERVMJHCHNTKO-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50135601   

TargetMatrix metalloproteinase-14(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50135601(N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 10nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50135601(N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 17nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50135601(N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50135601(N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 179nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50135601(N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 18nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50135601(N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50135601(N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 179nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed