BDBM50135421 Biphenyl-2-carboxylic acid [4-(2-dimethylaminomethyl-3,4-dihydro-2H-benzo[b][1,4]thiazepine-5-carbonyl)-phenyl]-amide::CHEMBL128687

SMILES CN(C)CC1CCN(C(=O)c2ccc(NC(=O)c3ccccc3-c3ccccc3)cc2)c2ccccc2S1

InChI Key InChIKey=ZOPTUHMWTVWMAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135421   

TargetVasopressin V2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135421(Biphenyl-2-carboxylic acid [4-(2-dimethylaminometh...)
Affinity DataIC50: 430nMAssay Description:Inhibition of vasopressin induced cAMP accumulation in human V2 receptor expressing cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135421(Biphenyl-2-carboxylic acid [4-(2-dimethylaminometh...)
Affinity DataIC50: 1.20E+3nMAssay Description:Ability to displace [3H]arginine vasopressin in cloned human V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed