BDBM50135289 (1S,2R,3S,4R)-4-(6-Amino-2-fluoro-purin-9-yl)-cyclopentane-1,2,3-triol::(1S,2R,3S,4R)-4-(6-amino-2-fluoro-9H-purin-9-yl)cyclopentane-1,2,3-triol::2-fluoronoraristeromycin::CHEMBL129469

SMILES Nc1nc(F)nc2n(cnc12)[C@@H]1C[C@H](O)[C@@H](O)[C@H]1O

InChI Key InChIKey=AJVKXNXJKJUXAE-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50135289   

TargetAdenosylhomocysteinase(Plasmodium falciparum (isolate 3D7))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135289(2-fluoronoraristeromycin | (1S,2R,3S,4R)-4-(6-amin...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory activity against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosylhomocysteinase(Human)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135289(2-fluoronoraristeromycin | (1S,2R,3S,4R)-4-(6-amin...)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of human SAHHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAdenosylhomocysteinase(Plasmodium falciparum (isolate 3D7))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135289(2-fluoronoraristeromycin | (1S,2R,3S,4R)-4-(6-amin...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of Plasmodium falciparum SAHHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAdenosylhomocysteinase(Human)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135289(2-fluoronoraristeromycin | (1S,2R,3S,4R)-4-(6-amin...)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibitory activity against human S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosylhomocysteinase(Human)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135289(2-fluoronoraristeromycin | (1S,2R,3S,4R)-4-(6-amin...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant SAHHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAdenosylhomocysteinase(Plasmodium falciparum (isolate 3D7))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135289(2-fluoronoraristeromycin | (1S,2R,3S,4R)-4-(6-amin...)
Affinity DataKi:  480nMAssay Description:Inhibitory activity against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosylhomocysteinase(Human)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135289(2-fluoronoraristeromycin | (1S,2R,3S,4R)-4-(6-amin...)
Affinity DataKi:  7.90E+3nMAssay Description:Inhibitory activity against human S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed