BDBM50135286 CHEMBL3745885
SMILES Cn1c2nc(Nc3ccc4[nH]ccc4c3)ncc2cc(c1=O)S(=O)(=O)c1ccc(F)cc1F
InChI Key InChIKey=ZEHBZHZMQSHZFI-UHFFFAOYSA-N
Data 337 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 337 hits for monomerid = 50135286
TargetMAP/microtubule affinity-regulating kinase 4(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MARK4 using [KKKVSRSGLYRSPSMPENLNRPR] as substrateMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MEK1 using ERK2 as substrateMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MEK2 using ERK2 as substrateMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 3(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MEK3 using p38alpha as substrateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 1(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MEKK1 using MBP as substrateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 2(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MEKK2 using MBP as substrateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 3(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MEKK3 using MBP as substrateMore data for this Ligand-Target Pair
TargetMaternal embryonic leucine zipper kinase(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MELK using [KKLNRTLSFAEPG] as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MINK using MBP as substrateMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MKK4More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 6(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MKK6 using p38alpha as substrateMore data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MLCK using [KKLNRTLSFAEPG] as substrateMore data for this Ligand-Target Pair
TargetMyosin light chain kinase 2, skeletal/cardiac muscle(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MLCK2 using [KKLNRTLSFAEPG] as substrateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MLK1 using casein as substrateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 10(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MLK2 using MBP as substrateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MLK3 using MBP as substrateMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MNK1 using MBP as substrateMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MNK2 using MBP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MRCKalpha using [KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK] as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase MRCK beta(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MRCKbeta using [KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK] as substrateMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-5(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MSK1 using [GRPRTSSFAEG] as substrateMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-4(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MSK2 using [GRPRTSSFAEG] as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MSSK1 using [GRSRSRSRSR] as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 4(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MST1 using [KKSRGDYMTMQIG] as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MST2 using MBP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 24(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MST3 using MBP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 26(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MST4 using MBP as substrateMore data for this Ligand-Target Pair
TargetMuscle, skeletal receptor tyrosine-protein kinase(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MUSK using MBP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MYLK3 using [KKLNRTLSFAEPG] as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MYO3b using MBP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek1(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of human NEK1 using MBP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek11(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NEK11 using MBP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of human NEK2 using MBP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek3(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NEK3 using MBP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek4(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NEK4 using MBP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek5(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of human NEK5 using MBP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek6(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NEK6 using MBP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek7(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NEK7 using MBP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek9(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human NEK9 using MBP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase NLK(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NLK using MBP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase OSR1(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human OSR1 using [RRHYYYDTHTNTYYLRTFGHNTRR] as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human P38alpha using MBP as substrateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human P38beta using MBP as substrateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 13(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human P38delta using MBP as substrateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 12(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human P38gamma using MBP as substrateMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human RPS6KB1 using [KKRNRTLTK] as substrateMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-2(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human RPS6KB2 using [KKRNRTLTK] as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 1(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PAK1 using [KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK] substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 2(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PAK2 using [KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK] substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 3(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PAK3 using [KKLNRTLSFAEPG] substrateMore data for this Ligand-Target Pair