BDBM50135226 CHEMBL3747473

SMILES COc1ccc(cc1)S(=O)(=O)N(Nc1ccccc1)C(=O)Oc1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=BMTQTIXCIMFTIQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50135226   

TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50135226(CHEMBL3747473)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PGES-1 in human A549 cell microsomes using PGH2 as substrate assessed as suppression of interleukin-1beta-stimulated PGE2 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50135226(CHEMBL3747473)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50135226(CHEMBL3747473)
Affinity DataIC50: 60nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50135226(CHEMBL3747473)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human COX2 by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed