BDBM50134952 CHEMBL443590::H-Tyr-Val-c[D-Cys-Gly-His-Phe-Arg-Trp-Cys]-Arg-Phe-Gly-NH2

SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O

InChI Key InChIKey=SMAWMSUKCNWJNR-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50134952   

TargetMelanocortin receptor 3(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50134952(H-Tyr-Val-c[D-Cys-Gly-His-Phe-Arg-Trp-Cys]-Arg-Phe...)
Affinity DataEC50: >1.00E+4nMAssay Description:Intracellular cAMP accumulation in human Melanocortin 3 receptor functional assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50134952(H-Tyr-Val-c[D-Cys-Gly-His-Phe-Arg-Trp-Cys]-Arg-Phe...)
Affinity DataEC50:  250nMAssay Description:Intracellular cAMP accumulation in Melanocortin 4 receptor functional assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50134952(H-Tyr-Val-c[D-Cys-Gly-His-Phe-Arg-Trp-Cys]-Arg-Phe...)
Affinity DataEC50: >1.00E+4nMAssay Description:Intracellular cAMP accumulation in human Melanocortin 5 receptor functional assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50134952(H-Tyr-Val-c[D-Cys-Gly-His-Phe-Arg-Trp-Cys]-Arg-Phe...)
Affinity DataKi:  460nMAssay Description:Binding affinity against Melanocortin 4 receptor by gamma-MCH displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50134952(H-Tyr-Val-c[D-Cys-Gly-His-Phe-Arg-Trp-Cys]-Arg-Phe...)
Affinity DataKi: >3.90E+3nMAssay Description:Binding affinity against human Melanocortin 5 receptor by gamma-MCH displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50134952(H-Tyr-Val-c[D-Cys-Gly-His-Phe-Arg-Trp-Cys]-Arg-Phe...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against human Melanocortin 3 receptor by gamma-MCH displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed