BDBM50134450 2-[1-(3-Hydroxy-4-methoxy-phenyl)-meth-(Z)-ylidene]-5,6,7-trimethoxy-benzofuran-3-one::CHEMBL126094

SMILES COc1ccc(\C=C2/Oc3c(cc(OC)c(OC)c3OC)C2=O)cc1O

InChI Key InChIKey=LZMHHIWFIGTABL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134450   

TargetTubulin alpha-1A chain(Pig)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50134450(2-[1-(3-Hydroxy-4-methoxy-phenyl)-meth-(Z)-ylidene...)
Affinity DataIC50: 2.20E+4nMAssay Description:Concentration that cause a 50% inhibition in tubulin assembly as measured by an increase in turbidity using microtubule assembly assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin alpha-1A/beta chain(Pig)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50134450(2-[1-(3-Hydroxy-4-methoxy-phenyl)-meth-(Z)-ylidene...)
Affinity DataIC50: 6.00E+4nMAssay Description:Ability to inhibit the binding of [3H]colchicine to porcine tubulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed