BDBM50134099 (3aR,10S)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione::CHEMBL337587::Trans-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione

SMILES CCCCn1c(O)c2Cc3c([nH]c4ccccc34)[C@H](c3ccc(OC)cc3)n2c1=O

InChI Key InChIKey=GKNMKFGNESPSPX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50134099   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134099((3aR,10S)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50134099((3aR,10S)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50134099((3aR,10S)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE2 (phosphodiesterase 2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50134099((3aR,10S)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine aorta PDE3 (phosphodiesterase 3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134099((3aR,10S)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134099((3aR,10S)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed