BDBM50133965 (S)-2-[(3aS,6S,6aR)-4-(5-Methoxy-thiazolo[5,4-b]pyridin-2-yl)-6-methyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl]-pyrrolidine-1-carboxylic acid (4-isopropyl-phenyl)-amide::CHEMBL344424

SMILES COc1ccc2nc(sc2n1)N1[C@H]2CCN([C@@H]2[C@H](C)C1=O)C(=O)[C@@H]1CCCN1C(=O)Nc1ccc(cc1)C(C)C

InChI Key InChIKey=CHMFMINHSDVAEL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133965   

TargetCapsid scaffolding protein(HHV-5)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50133965((S)-2-[(3aS,6S,6aR)-4-(5-Methoxy-thiazolo[5,4-b]py...)
Affinity DataIC50: 870nMAssay Description:Inhibition of human cytomegalovirus protease in HCMV pNA assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50133965((S)-2-[(3aS,6S,6aR)-4-(5-Methoxy-thiazolo[5,4-b]py...)
Affinity DataKi:  117nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed