BDBM50133332 CHEMBL3183233

SMILES COCCOc1nc(-c2ccc(Cl)c(Cl)c2)n(n1)-c1ccc(NC(=O)CCl)cc1

InChI Key InChIKey=TWJGQZBSEMDPQP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50133332   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Institute of Basic Science (Ibs)

Curated by ChEMBL
LigandPNGBDBM50133332(CHEMBL3183233)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of His-tagged human MALT1 (catalytic domain-339-719 aa) by fluorescence based assay using 25 uM Ac-LRSR-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Institute of Basic Science (Ibs)

Curated by ChEMBL
LigandPNGBDBM50133332(CHEMBL3183233)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2017
Entry Details Article
PubMed
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Institute of Basic Science (Ibs)

Curated by ChEMBL
LigandPNGBDBM50133332(CHEMBL3183233)
Affinity DataIC50: 7.76E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2017
Entry Details Article
PubMed
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Institute of Basic Science (Ibs)

Curated by ChEMBL
LigandPNGBDBM50133332(CHEMBL3183233)
Affinity DataIC50: 5.84E+3nMAssay Description:Inhibition of full length recombinant wild type MALT1 (unknown origin) using Ac-LVSR-AMC as substrate by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed