BDBM50133058 17,20,23,26-tetraoxa-4,12,14,29,31-pentaazahexacyclo[27.6.1.17,14.02,6.08,13.030,35]heptatriaconta-1(36),2(6),7(37),8,10,12,30,32,34-nonaene-3,5-dione::CHEMBL337642

SMILES O=C1NC(=O)C2=C1c1cn(CCOCCOCCOCCOCCn3cc2c2cccnc32)c2ncccc12

InChI Key InChIKey=GJJAFPBCJBFVII-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50133058   

TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50133058(17,20,23,26-tetraoxa-4,12,14,29,31-pentaazahexacyc...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50133058(17,20,23,26-tetraoxa-4,12,14,29,31-pentaazahexacyc...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50133058(17,20,23,26-tetraoxa-4,12,14,29,31-pentaazahexacyc...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50133058(17,20,23,26-tetraoxa-4,12,14,29,31-pentaazahexacyc...)
Affinity DataIC50: 48nMAssay Description:Inhibition of Glycogen synthase kinase-3beta (GSK3-beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50133058(17,20,23,26-tetraoxa-4,12,14,29,31-pentaazahexacyc...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Protein kinase C beta 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50133058(17,20,23,26-tetraoxa-4,12,14,29,31-pentaazahexacyc...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50133058(17,20,23,26-tetraoxa-4,12,14,29,31-pentaazahexacyc...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Protein kinase C thetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50133058(17,20,23,26-tetraoxa-4,12,14,29,31-pentaazahexacyc...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Protein kinase C gamma (PKC-gamma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50133058(17,20,23,26-tetraoxa-4,12,14,29,31-pentaazahexacyc...)
Affinity DataIC50: 34nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed