BDBM50132630 (2R,3S)-3,4-Dimethyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-2-carboxylic acid hydroxyamide::CHEMBL322705

SMILES C[C@H]1[C@@H](N(CCN1C)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1)C(=O)NO

InChI Key InChIKey=NOTPJXXSHYGYMI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132630   

LigandPNGBDBM50132630((2R,3S)-3,4-Dimethyl-1-[4-(2-methyl-benzyloxy)-ben...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant tumor necrosis factor-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50132630((2R,3S)-3,4-Dimethyl-1-[4-(2-methyl-benzyloxy)-ben...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of Tumor necrosis factor-alpha (TNF-alpha) release in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed