BDBM50132621 (2S,3R)-3-Hydroxycarbamoyl-2-methyl-4-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-1-carboxylic acid ethyl ester::CHEMBL109267

SMILES CCOC(=O)N1CCN([C@H]([C@@H]1C)C(=O)NO)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1

InChI Key InChIKey=FPHXOEUJYCDFQF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50132621   

LigandPNGBDBM50132621((2S,3R)-3-Hydroxycarbamoyl-2-methyl-4-[4-(2-methyl...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant tumor necrosis factor-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132621((2S,3R)-3-Hydroxycarbamoyl-2-methyl-4-[4-(2-methyl...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132621((2S,3R)-3-Hydroxycarbamoyl-2-methyl-4-[4-(2-methyl...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of matrix metalloprotease-13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50132621((2S,3R)-3-Hydroxycarbamoyl-2-methyl-4-[4-(2-methyl...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant tumor necrosis factor-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed