BDBM50132619 (2R,3S)-4-Benzyl-3-methyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-2-carboxylic acid hydroxyamide::CHEMBL325150

SMILES C[C@H]1[C@@H](N(CCN1Cc1ccccc1)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1)C(=O)NO

InChI Key InChIKey=NKDZJRDULDIJON-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132619   

TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132619((2R,3S)-4-Benzyl-3-methyl-1-[4-(2-methyl-benzyloxy...)
Affinity DataIC50: 1.70E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50132619((2R,3S)-4-Benzyl-3-methyl-1-[4-(2-methyl-benzyloxy...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant tumor necrosis factor-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50132619((2R,3S)-4-Benzyl-3-methyl-1-[4-(2-methyl-benzyloxy...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of Tumor necrosis factor-alpha (TNF-alpha) release in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed