BDBM50132461 2-(4-{2-tert-Butoxycarbonylamino-2-[4-(3-hydroxy-2-methoxycarbonyl-phenoxy)-butylcarbamoyl]-ethyl}-phenoxy)-malonic acid::CHEMBL104371

SMILES COC(=O)c1c(O)cccc1OCCCCNC(=O)C(Cc1ccc(OC(C(O)=O)C(O)=O)cc1)NC(=O)OC(C)(C)C

InChI Key InChIKey=GFLFMVSYYFLPFQ-UHFFFAOYSA-N

Data  6 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50132461   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132461(2-(4-{2-tert-Butoxycarbonylamino-2-[4-(3-hydroxy-2...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132461(2-(4-{2-tert-Butoxycarbonylamino-2-[4-(3-hydroxy-2...)
Affinity DataKi:  2.48E+4nMAssay Description:Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132461(2-(4-{2-tert-Butoxycarbonylamino-2-[4-(3-hydroxy-2...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against CD45 PhosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132461(2-(4-{2-tert-Butoxycarbonylamino-2-[4-(3-hydroxy-2...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against Tyrosine phosphatase SHP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132461(2-(4-{2-tert-Butoxycarbonylamino-2-[4-(3-hydroxy-2...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against LARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50132461(2-(4-{2-tert-Butoxycarbonylamino-2-[4-(3-hydroxy-2...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against Cell division cycle 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed