BDBM50132448 2-[3-(5-Methoxy-1-methyl-1H-indol-3-ylmethylene)-2-oxo-2,3-dihydro-1H-indole-5-sulfonylamino]-acetamide::CHEMBL108258

SMILES COc1ccc2n(C)cc(\C=C3/C(=O)Nc4ccc(cc34)S(=O)(=O)NCC(N)=O)c2c1

InChI Key InChIKey=BRYYLFIPPRHCLJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132448   

TargetTyrosine-protein kinase SYK(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132448(2-[3-(5-Methoxy-1-methyl-1H-indol-3-ylmethylene)-2...)
Affinity DataIC50: 98nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132448(2-[3-(5-Methoxy-1-methyl-1H-indol-3-ylmethylene)-2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed